Some people may know of this drug as OT-58, but it's proper name is TVT-058, Pegtibatinase,
In November 2020, Retrophin acquired Orphan Technologies, thus also acquiring OT-58 and their Natural History Study. Shortly after, Retrophin rebranded as Travere.
Travere Therapeutics is in the process of developing an enzyme replacement therapy for patients with CBS Deficiency Homocystinuria.
For the most up to date news on their enzyme replacement, please visit their website: Click here
October 27, 2022
Travere Therapeutics, Inc. today reported its third quarter 2022 financial results and provided a corporate update.
A Breakthrough Therapy Designation was granted to the pegtibatinase development program for classical homocystinuria (HCU).
August 25, 2022
Population-based Incidence Estimates of Classical Homocystinuria Using the Genome Aggregation Database (gnomAD)
A Longitudinal Study of Cognitive Function in Classical Homocystinuria Demonstrates Distinct Deficits in Inhibitory Control
- Insights from the First Genetic Evaluation of a Longitudinal Natural History Study in Classical Homocystinuria (HCU)
August 3, 2022
Pegtibatinase granted Breakthrough Therapy Designation by FDA